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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PCNA, proliferating cell nuclear antigen
Sequence ID:NM_002592
Entrez Gene ID:5111
Ensembl ID:ENSG00000132646

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20pter-p12

Chromosomal Position (from UCSC)

Chromosomal Position:20: 5098691 - 5107186

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820036Full LengthBC000491proliferating cell nuclear antigen
4102284Full LengthBC062439proliferating cell nuclear antigen

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002583  NP_872590  

Protein Infomation

NM_002592 NP_002583 P12004 PCNA_N
NM_182649 NP_872590 P12004 PCNA_N

Related Sequences

M15796 AAA35736 P12004
BC000491 AAH00491 P12004
BC062439 AAH62439 P12004
DQ891403 ABM82329  
DQ894581 ABM85507  
D28458 BAA05824  
AK313286 BAG36094 P12004
AK300558 BAG62264 B4DUA2
CR536501 CAG38740 Q6FI35
CR541799 CAG46598 Q6FHF5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PCNA NP_002583 R.norvegicus Pcna 25737   NP_071776 98
M.musculus Pcna 18538 Gene Info NP_035175 97
D.melanogaster mus209 37290   NP_476905 71
A.gambiae AgaP_AGAP010220 1279643   XP_319407 70
A.thaliana PCNA2 817506   NP_180517 66
A.thaliana PCNA1 837249   NP_172217 65
N.crassa NCU09239 3880823   XP_964674 55
S.pombe pcn1 2540020   NP_596504 52
S.cerevisiae POL30 852385   NP_009645 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta