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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PPP2R2A, protein phosphatase 2, regulatory subunit B, alpha
Sequence ID:NM_001177591
Entrez Gene ID:5520
Ensembl ID:ENSG00000221914

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 26218605 - 26228645

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5484483Full LengthBC041071protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002708  

Protein Infomation

NM_001177591 NP_001171062    
NM_002717 NP_002708 P63151 WD40

Related Sequences

M64929 AAA36490 P63151
BC041071 AAH41071 P63151
AY189686 AAO85219 Q56VW8
AK314823 BAG37345 P63151
AK303981 BAG64899 P63151

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPP2R2A NP_001171062 M.musculus Ppp2r2a 71978 Gene Info NP_082308 100
R.norvegicus Ppp2r2a 117104   NP_446451 100
C.elegans sur-6 172826   NP_492591 68
N.crassa NCU09377 3879897   XP_963748 61
S.pombe pab1 2541519   NP_592961 60
S.cerevisiae CDC55 852685   NP_011325 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)