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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP3K2, mitogen-activated protein kinase kinase kinase 2
Sequence ID:NM_006609
Entrez Gene ID:10746
Ensembl ID:ENSG00000169967

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q14.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 128063522 - 128096627

 Exon Info From UCSC:
NM_006609

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020280Full LengthBC136293mitogen-activated protein kinase kinase kinase 2
4284906IncompleteBC065755mitogen-activated protein kinase kinase kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006600  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006609 NP_006600 Q9Y2U5 EC 2.7.11.25 Pkinase
PB1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF111105 AAD28547 Q9Y2U5 EC 2.7.11.25
AF239798 AAF63496 Q9Y2U5 EC 2.7.11.25
BC065755 AAH65755 Q6P084  
BC136293 AAI36294 Q9Y2U5 EC 2.7.11.25
AK027345 BAB55050 Q96K88  
AK075004 BAC11348 Q9Y2U5 EC 2.7.11.25
AB208963 BAD92200 Q9Y2U5 EC 2.7.11.25

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP3K2 NP_006600 M.musculus Map3k2 26405 Gene Info NP_036076 96
R.norvegicus Map3k2 171492   NP_612512 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta