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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. KCNMA1, Potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Sequence ID:NM_001014797
NM_001161352
NM_001161353
NM_002247
RefSeqGene ID:NG_012270
Entrez Gene ID:3778
Ensembl ID:ENSG00000156113

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GENERALIZED EPILEPSY AND PAROXYSMAL DYSKINESIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 78646925 - 79397342

 Exon Info From UCSC:
NM_001014797
NM_001161352
NM_001161353
NM_002247

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021112Full LengthBC137115potassium large conductance calcium-activated channel, subfamily M, alpha member 1
9021134Full LengthBC137137potassium large conductance calcium-activated channel, subfamily M, alpha member 1
9053023Full LengthBC144496potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002238  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001014797 NP_001014797    
NM_001161352 NP_001154824 Q12791  
NM_001161353 NP_001154825    
NM_001271518 NP_001258447    
NM_001271519 NP_001258448    
NM_001271520 NP_001258449    
NM_001271521 NP_001258450    
NM_001271522 NP_001258451    
NM_002247 NP_002238   Ion_trans
BK_channel_a

Related Sequences

 
mRNAGenPeptSwissProt
U02632 AAA50173 Q12791
Q5JQ19
U09384 AAA50216 Q12791
U13913 AAA85104 Q12791
U23767 AAA92290 Q12791
U11058 AAB65837 Q12791
AF025999 AAB88802 Q12791
U11717 AAC50353 Q12791
AF118141 AAD31173 Q12791
BC062659 AAH62659 Q12791
BC137115 AAI37116 Q12791
BC137137 AAI37138 Q12791
BC144496 AAI44497 B7ZMF5
AF349445 AAK30158 Q9BX94
AY040849 AAK91504 Q12791
AY445624 AAS01054 Q6JJ72
AB113382 BAD06365 Q12791
AB113575 BAD06397 Q12791
AB209488 BAD92725 Q59FH2
AB524033 BAJ07308 D5MRH1
CR627384 CAH10480 Q6AI34

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KCNMA1 NP_001154824 M.musculus Kcnma1 16531 Gene Info NP_034740 99
R.norvegicus Kcnma1 83731   NP_114016 99
A.gambiae AgaP_AGAP003709 1274388   XP_313505 61
D.melanogaster slo 42940   NP_001014657 60
C.elegans slo-1 180203   NP_001024259 58

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)