Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AGXT, alanine-glyoxylate aminotransferase
Sequence ID:NM_000030
RefSeqGene ID:NG_008005
Entrez Gene ID:189
Ensembl ID:ENSG00000172482

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPEROXALURIA, PRIMARY, TYPE 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q37.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 241808260 - 241818523

 Exon Info From UCSC:
NM_000030

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146841Full LengthBC132819alanine-glyoxylate aminotransferase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000021  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000030 NP_000021 P21549 EC 2.6.1.51
EC 2.6.1.44
Aminotran_5

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S71388 AAB20488 Q16171  
AF191687 AAF05604 Q9UJX1  
BC132819 AAI32820 P21549 EC 2.6.1.51
EC 2.6.1.44
AF348451 AAK30157 Q9BXA1  
D13368 BAA02632 P21549 EC 2.6.1.51
EC 2.6.1.44
AB292648 BAF46862 A2V838  
AK292754 BAF85443 P21549 EC 2.6.1.51
EC 2.6.1.44
AK315331 BAG37731 B2RCY4  
AK298400 BAH12776 B7Z540  
AK298420 BAH12784 B7Z548  
AK316495 BAH14866 B7Z540  
X53414 CAA37493 P21549 EC 2.6.1.51
EC 2.6.1.44
X56092 CAA39572 P21549 EC 2.6.1.51
EC 2.6.1.44

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AGXT NP_000021 R.norvegicus Agxt 24792   NP_085914 79
M.musculus Agxt 11611 Gene Info NP_057911 77
A.gambiae AgaP_AGAP003490 1270941   XP_309676 46
D.melanogaster Spat 31587   NP_511062 46
C.elegans T14D7.1 174414   NP_495885 44
A.thaliana AGT 815822   NP_849951 33
N.crassa NCU01821 3872065   XP_955918 28
S.cerevisiae AGX1 850514   NP_116623 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)