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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. CASP3, caspase 3, apoptosis-related cysteine peptidase
Sequence ID:NM_004346
Entrez Gene ID:836
Ensembl ID:ENSG00000164305

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 185550425 - 185559607

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4419175Full LengthBC016926caspase 3, apoptosis-related cysteine peptidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_116786  NP_004337  

Protein Infomation

NM_004346 NP_004337 P42574 EC Peptidase_C14
NM_032991 NP_116786 P42574 EC Peptidase_C14

Related Sequences

U13737 AAA65015 P42574 EC
U26943 AAA74929 P42574 EC
U13738 AAB60355 P42574 EC
BC016926 AAH16926 P42574 EC
DQ891543 ABM82469    
DQ894731 ABM85657    
AK291337 BAF84026 P42574 EC
AJ413269 CAC88866 P42574 EC
BX647609 CAI46084 Q5HYI3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CASP3 NP_004337 R.norvegicus Casp3 25402   NP_037054 89
M.musculus Casp3 12367 Gene Info NP_033940 87
A.gambiae CASPS11 1275726   XP_315012 43
A.gambiae CASPS4 1280719   XP_320581 41
A.gambiae AgaP_AGAP012945 4397760   XP_001230552 41
A.gambiae CASPS6 1275724   XP_315010 40
A.gambiae CASPS5 1275725   XP_315011 39
A.gambiae CASPS3 1280718   XP_320580 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta