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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CASP4, caspase 4, apoptosis-related cysteine peptidase
Sequence ID:NM_001225
NM_033306
NM_033307
Entrez Gene ID:837
Ensembl ID:ENSG00000196954

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q22.2-q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 104813599 - 104840163

 Exon Info From UCSC:
NM_001225
NM_033306

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4699374Full LengthBC017839caspase 4, apoptosis-related cysteine peptidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_150649  NP_001216  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001225 NP_001216 P49662 EC 3.4.22.57 CARD
Peptidase_C14
NM_033306 NP_150649     Peptidase_C14

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U28014 AAA75171 P49662 EC 3.4.22.57
U25804 AAA86890 P49662 EC 3.4.22.57
U28976 AAC99850 P49662 EC 3.4.22.57
U28977 AAC99851 A2NHL9  
U28978 AAC99852 P49662 EC 3.4.22.57
U28979 AAC99853 O95601  
U28979 AAC99854 Q7KYX7  
BC017839 AAH17839 P49662 EC 3.4.22.57
DQ891983 ABM82909    
DQ895173 ABM86099    
AK057094 BAG51861 B3KPZ9  
AK296081 BAG58837 B4DJH5  
AK304222 BAG65094 B4E2D2  
Z48810 CAA88750 P49662 EC 3.4.22.57
AL050391 CAB43686 Q9UG96  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CASP4 NP_001216 M.musculus Casp4 12363 Gene Info NP_031635 60
R.norvegicus Casp4 114555   NP_446188 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta