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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAPK8, mitogen-activated protein kinase 8
Sequence ID:NM_002750
NM_139046
NM_139047
NM_139049
RefSeqGene ID:NG_029053
Entrez Gene ID:5599
Ensembl ID:ENSG00000107643

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 49609703 - 49642936

 Exon Info From UCSC:
NM_002750
NM_139046
NM_139047
NM_139049

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052583Full LengthBC144063mitogen-activated protein kinase 8
40146601Full LengthBC130570mitogen-activated protein kinase 8
40146603Full LengthBC130572mitogen-activated protein kinase 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002741  NP_620637  NP_620635  NP_620634  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002750 NP_002741     Pkinase
NM_139046 NP_620634     Pkinase
Pkinase_Tyr
NM_139047 NP_620635     Pkinase
Pkinase_Tyr
NM_139049 NP_620637 P45983 EC 2.7.11.24 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L26318 AAA36131 P45983 EC 2.7.11.24
U34822 AAC50607 P45983 EC 2.7.11.24
U35004 AAC50610 P45983 EC 2.7.11.24
U35005 AAC50611 P45983 EC 2.7.11.24
BC130570 AAI30571 A1L4K2  
BC130572 AAI30573 A1L4K2  
BC144063 AAI44064 P45983 EC 2.7.11.24
DQ234352 ABB29981 Q308M2  
HQ258413 ADR83167    
AK292523 BAF85212 A1L4K2  
AB451231 BAG70045 P45983 EC 2.7.11.24
AB451271 BAG70085 A1L4K2  
AB451354 BAG70168 B5BUB8  
AB451398 BAG70212 A1L4K2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAPK8 NP_620637 M.musculus Mapk8 26419 Gene Info NP_057909 100
R.norvegicus Mapk8 116554   XP_341400 96
A.gambiae AgaP_AGAP009461 1271440   XP_310236 80
D.melanogaster bsk 44801   NP_001162930 78
C.elegans jnk-1 177460   NP_001021270 71

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta