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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HUWE1, HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
Sequence ID:NM_031407
RefSeqGene ID:NG_016261
Entrez Gene ID:10075
Ensembl ID:ENSG00000086758

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp11.22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 53559058 - 53620561

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3140705IncompleteBC002602HECT, UBA and WWE domain containing 1
3345717IncompleteBC018750HECT, UBA and WWE domain containing 1
3451298IncompleteBC063505HECT, UBA and WWE domain containing 1
4292231IncompleteBC107576HECT, UBA and WWE domain containing 1
4577920IncompleteBC038184HECT, UBA and WWE domain containing 1
6185133IncompleteBC072421HECT, UBA and WWE domain containing 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_113584  

Protein Infomation

NM_031407 NP_113584 Q7Z6Z7 UBA

Related Sequences

AF057569 AAC62492 Q7Z6Z7
AF161390 AAF28950 Q7Z6Z7
BC002602 AAH02602 Q7Z6Z7
BC018750 AAH18750 Q8IWJ0
BC038184 AAH38184 Q8IWJ0
BC063505 AAH63505 Q7Z6Z7
BC107576 AAI07577 Q3B7K0
AY772009 AAV90838 Q7Z6Z7
AY929612 AAX24125 Q7Z6Z7
DQ097177 AAY98258 Q7Z6Z7
AB002310 BAA20771 Q7Z6Z7
AB071605 BAC06833 Q7Z6Z7
AK223167 BAD96887 Q53FW4
AK294575 BAG57767 B4DGF6
AL162050 CAB82393 Q7Z6Z7
CR456813 CAG33094 Q7Z6Z7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HUWE1 NP_113584 M.musculus Huwe1 59026 Gene Info NP_067498 98
D.melanogaster CG8184 32510   NP_573059 42
C.elegans eel-1 177084   NP_500284 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)