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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYP2B6, cytochrome P450, family 2, subfamily B, polypeptide 6
Sequence ID:NM_000767
RefSeqGene ID:NG_007929
Entrez Gene ID:1555
Ensembl ID:ENSG00000197408

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EFAVIRENZ CENTRALNERVOUS SYSTEM TOXICITY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 41497208 - 41522774

NM_000767 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11784149720341497380
1793414150990541510067
3424914151020141510350
4926524151280941512969
6538294151512341515299
8309714151589841516039
97211594151820241518389
116013014151857841518719
130230524152255041524300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7002137Full LengthBC067430cytochrome P450, family 2, subfamily B, polypeptide 6
7002142Full LengthBC067431cytochrome P450, family 2, subfamily B, polypeptide 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000758  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000767 NP_000758 P20813 p450

Related Sequences

 
mRNAGenPeptSwissProt
M29874 AAA52144 P20813
AF182277 AAF13602 P20813
BC067430 AAH67430 Q6NWU2
BC067431 AAH67431 Q6NWU1
AK301620 BAG63105 B4DWP3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP2B6 NP_000758 M.musculus Cyp2b10 13088 Gene Info NP_034129 78
R.norvegicus Cyp2b1 24300   NP_001128316 76
R.norvegicus Cyp2b2 361523   XP_001062335 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta