Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SLC6A4, Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Sequence ID:NM_001045
RefSeqGene ID:NG_011747
Entrez Gene ID:6532
Ensembl ID:ENSG00000108576

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ANXIETY-RELATED PERSONALITY TRAITS 
OBSESSIVE-COMPULSIVE DISORDERBDNF
HTR2A

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 28525512 - 28562716

 Exon Info From UCSC:
NM_001045

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262380Full LengthBC069484solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001036  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001045 NP_001036 P31645 SNF
5HT_transporter

Related Sequences

 
mRNAGenPeptSwissProt
L05568 AAA35492 P31645
BC069484 AAH69484 P31645
AY902473 AAW80933 P31645
AK313166 BAG35984 B2R7Y7
X70697 CAA50029 P31645

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SLC6A4 NP_001036 M.musculus Slc6a4 15567 Gene Info NP_034614 93
R.norvegicus Slc6a4 25553   NP_037166 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)