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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TTN, titin
Sequence ID:NM_001256850
NM_001267550
NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
RefSeqGene ID:NG_011618
Entrez Gene ID:7273
Ensembl ID:ENSG00000155657

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 9 
CARDIOMYOPATHY,DILATED, 1G 
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2J 
MYOPATHY, EARLY-ONSET, WITH FATAL CARDIOMYOPATHY 
MYOPATHY, PROXIMAL,WITH EARLY RESPIRATORY MUSCLE INVOLVEMENT 
TIBIAL MUSCULAR DYSTROPHY, TARDIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 179522653 - 179536824

 Exon Info From UCSC:
NM_003319
NM_133378
NM_133379
NM_133432
NM_133437

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4246573IncompleteBC030823titin
4271100IncompleteBC026297titin
4271154IncompleteBC107797titin
4271838IncompleteBC070170titin
4288662IncompleteBC058824titin

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001256850 NP_001243779 Q8WZ42 EC 2.7.11.1  
NM_001267550 NP_001254479      
NM_003319 NP_003310      
NM_133378 NP_596869      
NM_133379 NP_596870      
NM_133432 NP_597676      
NM_133437 NP_597681      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC013396 AAH13396 Q8WZ42 EC 2.7.11.1
BC058824 AAH58824 Q8WZ42 EC 2.7.11.1
BC070170 AAH70170 Q8WZ42 EC 2.7.11.1
BC107797 AAI07798 Q8WZ42 EC 2.7.11.1
AF525413 AAP80791 Q8WZ42 EC 2.7.11.1
AF321609 AAT09768 Q71S18  
DQ248309 ABB55264 Q8WZ42 EC 2.7.11.1
EF212153 ABN05229 A2TKE3  
EF212154 ABN05230 A2TKE4  
EF212155 ABN05231 A2TKE5  
EF212156 ABN05232 A2TKE6  
EU428784 ACA00206 B1A7R7  
AK092284 BAC03850 Q8N237  
X64697 CAA45938 Q8WZ42 EC 2.7.11.1
X64698 CAA45939 Q8WZ42 EC 2.7.11.1
X69490 CAA49245 Q8WZ42 EC 2.7.11.1
X83270 CAA58243 Q8WZ42 EC 2.7.11.1
X90568 CAA62188 Q8WZ42 EC 2.7.11.1
X90569 CAA62189 Q8WZ42 EC 2.7.11.1
X98114 CAA66795 Q8WZ42 EC 2.7.11.1
X98115 CAA66796 Q8WZ42 EC 2.7.11.1
AL713647 CAD28458 Q8WZ42 EC 2.7.11.1
BX537998 CAD97954 Q7Z3B7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TTN NP_596869 M.musculus Ttn 22138 Gene Info NP_035782 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)