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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DISC1, Disrupted in schizophrenia 1
Sequence ID:NM_001164537
NM_018662
NM_001012957
NM_001164540
NM_001164538
NM_001164541
NM_001164550
NM_001164552
NM_001164544
NM_001164542
NM_001164553
NM_001164539
NM_001164547
NM_005999
NM_001164545
NM_001012958
NM_001164548
NM_001164546
NM_001164549
NM_001012959
NM_001164551
NM_001164555
NM_001164554
NM_001164556
RefSeqGene ID:NG_011681
Entrez Gene ID:27185
Ensembl ID:ENSG00000162946

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
SCHIZOAFFECTIVEDISORDERAKT1
APOL1
APOL2
APOL4
CHI3L1
CHI3L1
COMT
DAO
DAOA
DISC2
DRD3
DTNBP1
HTR2A
LGR4
MTHFR
MTHFR
RTN4R
SYN2
SCHIZOPHRENIARGS4

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 231762574 - 232176872

 Exon Info From UCSC:
NM_001164537
NM_018662
NM_001012957
NM_001164540
NM_001164538
NM_001164541
NM_001164550
NM_001164552
NM_001164544
NM_001164542
NM_001164553
NM_001164539
NM_001164547
NM_005999
NM_001164545
NM_001012958
NM_001164548
NM_001164546
NM_001164549
NM_001012959
NM_001164551
NM_001164555
NM_001164554
NM_001164556

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9007180Full LengthBC151225disrupted in schizophrenia 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005990  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001012957 NP_001012975    
NM_001012958 NP_001012976    
NM_001012959 NP_001012977    
NM_001164537 NP_001158009    
NM_001164538 NP_001158010    
NM_001164539 NP_001158011    
NM_001164540 NP_001158012    
NM_001164541 NP_001158013    
NM_001164542 NP_001158014    
NM_001164544 NP_001158016    
NM_001164545 NP_001158017    
NM_001164546 NP_001158018    
NM_001164547 NP_001158019    
NM_001164548 NP_001158020    
NM_001164549 NP_001158021    
NM_001164550 NP_001158022    
NM_001164551 NP_001158023    
NM_001164552 NP_001158024    
NM_001164553 NP_001158025    
NM_001164554 NP_001158026    
NM_001164555 NP_001158027    
NM_001164556 NP_001158028    
NM_005999 NP_005990 Q99598 Translin
NM_018662 NP_061132 Q9NRI5  

Related Sequences

 
mRNAGenPeptSwissProt
AF222980 AAF73889 Q9NRI5
BC010376 AAH10376 Q99598
BC011797 AAH11797 Q99598
BC151225 AAI51226 A7E2W8
FJ804174 ACR40040 C4P091
FJ804175 ACR40041 C4P092
FJ804176 ACR40042 C4P093
FJ804177 ACR40043 C4P094
FJ804178 ACR40044 Q9NRI5
FJ804179 ACR40045 C4P096
FJ804180 ACR40046 C4P091
FJ804181 ACR40047 C4P098
FJ804182 ACR40048 C4P091
FJ804183 ACR40049 C4P0A0
FJ804184 ACR40050 Q9NRI5
FJ804185 ACR40051 C4P093
FJ804186 ACR40052 Q9NRI5
FJ804187 ACR40053 C4P0A4
FJ804188 ACR40054 C4P0A5
FJ804189 ACR40055 C4P093
FJ804190 ACR40056 Q9NRI5
FJ804191 ACR40057 C4P091
FJ804192 ACR40058 C4P0A9
FJ804193 ACR40059 C4P0B0
FJ804194 ACR40060 C4P0B1
FJ804195 ACR40061 C4P0B2
FJ804196 ACR40062 Q9NRI5
FJ804197 ACR40063 C4P091
FJ804198 ACR40064 C4P092
FJ804199 ACR40065 C4P0B6
FJ804200 ACR40066 C4P091
FJ804201 ACR40067 C4P093
FJ804202 ACR40068 C4P0A5
FJ804203 ACR40069 C4P091
FJ804204 ACR40070 C4P0C1
FJ804205 ACR40071 Q9NRI5
FJ804206 ACR40072 C4P0B0
FJ804207 ACR40073 C4P0C4
FJ804208 ACR40074 C4P091
FJ804209 ACR40075 C4P092
FJ804210 ACR40076 C4P0C7
FJ804211 ACR40077 C4P0C8
FJ804212 ACR40078 C4P091
FJ804213 ACR40079 C4P0D0
FJ804214 ACR40080 C4P0D1
FJ804215 ACR40081 C4P0D2
FJ804216 ACR40082 C4P0D3
AB007926 BAA32302 Q9NRI5
AK313068 BAG35896 Q99598
X95073 CAA64469 Q99598
AJ506178 CAD44628 Q9NRI5
AJ506177 CAD44631 Q9NRI5
BX537610 CAD97797 Q7Z3N9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DISC1 NP_001012975 M.musculus Disc1 244667 Gene Info NP_777279 59
R.norvegicus Disc1 307940   NP_783186 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)