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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DFFB, DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Sequence ID:NM_004402
NM_001004285
NM_001004286
Entrez Gene ID:1677
Ensembl ID:ENSG00000169598

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 3774167 - 3800305

Transcript StartTranscript EndChromosomal Start Chromosomal End
143737738443774280
43856437752813775407
56575337823753782563
75483337845373784616
834100437861683786338
1005110537890353789135
1106302738000703801991

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5204996Full LengthBC048797DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004393  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004402 NP_004393 O76075 CIDE-N
NM_014704 NP_055519 O60308 HEAT

Related Sequences

 
mRNAGenPeptSwissProt
AF039210 AAC39709 O76075
AF064019 AAC39920 O76075
BC001640 AAH01640 O60308
BC032827 AAH32827 Q96P73
BC047450 AAH47450 O60308
BC048797 AAH48797 O76075
BC050721 AAH50721 O60308
AF409060 AAL02005 Q96P74
AF409061 AAL02006 Q96P73
AF409062 AAL02007 Q96P72
AY438267 AAR05821  
AY438268 AAR05822  
AB011134 BAA25488 O60308
AB013918 BAA32250 O76075
AB028911 BAB40447 O76075
AB028912 BAB40448 O76075
AB028913 BAB40449 O76075
AK290877 BAF83566 O76075
AK303065 BAG64182 B4DZS0
AK302190 BAH13645 B7Z7K9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DFFB NP_004393 M.musculus Dffb 13368 Gene Info NP_031885 78
R.norvegicus Dffb 84359   NP_445814 77
D.melanogaster Drep-4 34734   NP_609631 36
A.gambiae AgaP_AGAP009681 1279069   XP_318738 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta