Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MET, met proto-oncogene (hepatocyte growth factor receptor)
Sequence ID:NM_000245
NM_001127500
RefSeqGene ID:NG_008996
Entrez Gene ID:4233
Ensembl ID:ENSG00000105976

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AUTISM SUSEPTIBILITY 9 
HEPATOBLASTOMA, SOMATICAPC
APC
AXIN1
CASP8
CTNNB1
PDGFRL
PIK3CA
PIK3CA
TP53
TP53
RENAL CELL CARCINOMA, PAPILLARYPRCC
TFE3

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 116340161 - 116438439

 Exon Info From UCSC:
NM_000245
NM_001127500

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146451Full LengthBC130420met proto-oncogene (hepatocyte growth factor receptor)
3851374IncompleteBC027979met proto-oncogene (hepatocyte growth factor receptor)
4452921IncompleteBC016592met proto-oncogene (hepatocyte growth factor receptor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000236  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000245 NP_000236 P08581 EC 2.7.10.1 Pkinase
Sema
PSI
TIG
Pkinase_Tyr
NM_001127500 NP_001120972      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M35074 AAA59590 P08581 EC 2.7.10.1
J02958 AAA59591 P08581 EC 2.7.10.1
U11813 AAA68513 Q9UMU9  
BC027979 AAH27979 A0PJF7  
BC130420 AAI30421 P08581 EC 2.7.10.1
EU176015 ABX52004 E6Y365  
EU826567 ACF47603 B5A929  
EU826568 ACF47604 B5A930  
EU826569 ACF47605 B5A931  
EU826570 ACF47606 P08581 EC 2.7.10.1
EU826571 ACF47607 B5A933  
EU826572 ACF47608 B5A934  
EU826573 ACF47609 B5A935  
EU826574 ACF47610 B5A936  
EU826575 ACF47611 B5A937  
EU826576 ACF47612 B5A938  
EU826577 ACF47613 B5A939  
EU826579 ACF47615 B5A941  
EU826580 ACF47616 B5A942  
EU826581 ACF47617 B5A943  
AB209898 BAD93135 Q59EB3  
AK296974 BAG59517 B4DLF5  
AK298552 BAG60748 B4DPY6  
X54559 CAB56793 P08581 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MET NP_001120972 M.musculus Met 17295 Gene Info NP_032617 90
R.norvegicus Met 24553   NP_113705 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta