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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PIK3R1, phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Sequence ID:NM_001242466
NM_181504
NM_181523
NM_181524
RefSeqGene ID:NG_012849
Entrez Gene ID:5295
Ensembl ID:ENSG00000145675

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 67584251 - 67594401

 Exon Info From UCSC:
NM_181504
NM_181523
NM_181524

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4290954Full LengthBC030815phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
30528412Full LengthBC094795phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_852556  NP_852664  NP_852665  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001242466 NP_001229395    
NM_181504 NP_852556   SH2
NM_181523 NP_852664 P27986 SH2
SH3_1
RhoGAP
NM_181524 NP_852665   SH2

Related Sequences

 
mRNAGenPeptSwissProt
U49349 AAB04140 P27986
BC030815 AAH30815 P27986
BC094795 AAH94795 P27986
AF279367 AAO15359 P27986
HQ447692 ADQ32177  
JX133164 AFP86291 J7GXU7
JX133165 AFP86292 J7GU64
AK223613 BAD97333 P27986
AK094785 BAG52931 B3KT19
AK126345 BAG54309 B3KWZ7
AK294919 BAH11924 B7Z2N8
AK299743 BAH13115 B7Z629

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PIK3R1 NP_852664 M.musculus Pik3r1 18708 Gene Info NP_001070963 96
R.norvegicus Pik3r1 25513   NP_037137 94
C.elegans aap-1 172141   NP_491522 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta