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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. F12, coagulation factor XII (Hageman factor)
Sequence ID:NM_000505
RefSeqGene ID:NG_007568
Entrez Gene ID:2161
Ensembl ID:ENSG00000131187

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ANGIOEDEMA, HEREDITARY, TYPE III 
FACTOR XII DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q33-qterMitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 176829140 - 176836577

 Exon Info From UCSC:
NM_000505

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100068277Full LengthBC168381coagulation factor XII (Hageman factor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000496  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000505 NP_000496 P00748 EC 3.4.21.38 EGF
fn1
fn2
Kringle
Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M11723 AAA51986 P00748 EC 3.4.21.38
M13147 AAA70224 P00748 EC 3.4.21.38
M31315 AAA70225 P00748 EC 3.4.21.38
BC012390 AAH12390 Q96EF3  
BC168381 AAI68381 P00748 EC 3.4.21.38
BT007350 AAP36014 Q96EF3  
AB095845 BAC23095 Q8IZZ5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens F12 NP_000496 R.norvegicus F12 306761   NP_001014028 73
M.musculus F12 58992 Gene Info NP_067464 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta