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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. EIF2AK2, eukaryotic translation initiation factor 2-alpha kinase 2
Sequence ID:NM_001135651
NM_001135652
NM_002759
RefSeqGene ID:NG_030351
Entrez Gene ID:5610
Ensembl ID:ENSG00000055332

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2p22-p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 37334623 - 37347277

 Exon Info From UCSC:
NM_001135651
NM_001135652
NM_002759

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7939521Full LengthBC093676eukaryotic translation initiation factor 2-alpha kinase 2
8068981Full LengthBC101475eukaryotic translation initiation factor 2-alpha kinase 2
9051731Full LengthBC143230eukaryotic translation initiation factor 2-alpha kinase 2
4298375IncompleteBC007769eukaryotic translation initiation factor 2-alpha kinase 2
4720477IncompleteBC022314eukaryotic translation initiation factor 2-alpha kinase 2
4943987IncompleteBC040851eukaryotic translation initiation factor 2-alpha kinase 2
5278139IncompleteBC057805eukaryotic translation initiation factor 2-alpha kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002750  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135651 NP_001129123      
NM_001135652 NP_001129124      
NM_002759 NP_002750 P19525 EC 2.7.11.1
EC 2.7.10.2
dsrm
Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M85294 AAA18253 P19525 EC 2.7.11.1
EC 2.7.10.2
M35663 AAA36409 P19525 EC 2.7.11.1
EC 2.7.10.2
BC007769 AAH07769 Q6PK38  
BC022314 AAH22314 Q05CP4  
BC040851 AAH40851 Q8IW76  
BC057805 AAH57805 Q8IW76  
BC093676 AAH93676 P19525 EC 2.7.11.1
EC 2.7.10.2
BC101475 AAI01476 P19525 EC 2.7.11.1
EC 2.7.10.2
BC143230 AAI43231 B7ZKK7  
AY302136 AAP57628 Q7Z6F6  
AK290655 BAF83344 P19525 EC 2.7.11.1
EC 2.7.10.2
AK313818 BAG36554 P19525 EC 2.7.11.1
EC 2.7.10.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2AK2 NP_001129123 R.norvegicus Eif2ak2 54287   NP_062208 63
M.musculus Eif2ak2 19106 Gene Info NP_035293 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta