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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MVK, mevalonate kinase
Sequence ID:NM_000431
NM_001114185
RefSeqGene ID:NG_007702
Entrez Gene ID:4598
Ensembl ID:ENSG00000110921

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPER-IGD SYNDROME 
MEVALONIC ACIDURIA 
POROKERATOSIS 3, DISSEMINATED SUPERFICIAL ACTINICSART3

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 110011617 - 110035065

 Exon Info From UCSC:
NM_000431
NM_001114185

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3921543Full LengthBC016140mevalonate kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000422  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000431 NP_000422 Q03426 EC 2.7.1.36 GHMP_kinases_N
GHMP_kinases_C
NM_001114185 NP_001107657      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M88468 AAB59362 Q03426 EC 2.7.1.36
AF217536 AAF82406    
BC016140 AAH16140 Q03426 EC 2.7.1.36
DQ891089 ABM82015    
DQ894271 ABM85197    
AB209722 BAD92959 Q59ET9  
AK315678 BAG38043 B2RDU6  
AK293130 BAH11458 B7Z1C2  
AK295338 BAH12037 B7Z301  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MVK NP_000422 M.musculus Mvk 17855 Gene Info NP_076045 81
A.thaliana MK 832804   NP_001190411 42
C.elegans Y42G9A.4 175863   NP_001022867 41
S.pombe erg12 2542818   NP_592837 39
N.crassa NCU03633 3877492   XP_961360 37
S.cerevisiae ERG12 855248   NP_013935 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)