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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PPM1A, Protein phosphatase, Mg2+/Mn2+ dependent, 1A
Sequence ID:NM_021003
RefSeqGene ID:NG_029698
Entrez Gene ID:5494
Ensembl ID:ENSG00000100614

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 60749421 - 60759200

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3847638Full LengthBC026691protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
6011486Full LengthBC063243protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066283  NP_808821  NP_808820  

Protein Infomation

NM_021003 NP_066283 P35813 EC PP2C
NM_177951 NP_808820     PP2C
NM_177952 NP_808821 P35813 EC PP2C

Related Sequences

S87759 AAB21784 P35813 EC
AF070670 AAC28354 P35813 EC
BC026691 AAH26691 P35813 EC
BC063243 AAH63243 P35813 EC
AY236965 AAQ20086 Q5JB49  
DQ891766 ABM82692    
DQ894950 ABM85876    
AK313337 BAG36141 B2R8E4  
AB451247 BAG70061 P35813 EC
AB451371 BAG70185 B5BUD5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPM1A NP_808821 R.norvegicus Ppm1a 24666   NP_058734 99
M.musculus Ppm1a 19042 Gene Info NP_032936 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)