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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. AIRE, autoimmune regulator
Sequence ID:NM_000383
NM_000658
NM_000659
RefSeqGene ID:NG_009556
Entrez Gene ID:326
Ensembl ID:ENSG00000160224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AUTOIMMUNE POLYENDOCRINOPATHY SYNDROME , TYPE I, WITH OR WITHOUTREVERSIBLE METAPHYSEAL DYSPLASIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 45705762 - 45717872

 Exon Info From UCSC:
NM_000383
NM_000658

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021265Full LengthBC137268autoimmune regulator
9021267Full LengthBC137270autoimmune regulator

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000374  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000383 NP_000374 O43918 PHD
SAND
Sp100

Related Sequences

 
mRNAGenPeptSwissProt
BC137268 AAI37269 O43918
BC137270 AAI37271 O43918
AB006682 BAA23988 O43918
AB006683 BAA23989 O43918
AB006685 BAA23993 O43918
Z97990 CAB10790 O43918

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AIRE NP_000374 M.musculus Aire 11634 Gene Info NP_033776 73
R.norvegicus Aire 294328   NP_001099849 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)