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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PAX4, paired box 4
Sequence ID:NM_006193
RefSeqGene ID:NG_012848
Entrez Gene ID:5078
Ensembl ID:ENSG00000106331

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, KETOSIS-PRONE 
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE IX 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 127250864 - 127255982

NM_006193 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1915127250345127251259
9161057127251588127251729
10581113127251998127252053
11141183127253075127253144
11841266127253503127253585
12671392127253809127253934
13931468127254535127254610
14691684127254933127255148
16852010127255454127255779

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915220Full LengthBC074761paired box 4
40032097Full LengthBC107149paired box 4
40032102Full LengthBC107150paired box 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006184  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006193 NP_006184   Homeobox
PAX

Related Sequences

 
mRNAGenPeptSwissProt
AF043978 AAD02289 O43316
BC074761 AAH74761 O43316
BC107149 AAI07150 Q3KNR5
BC107150 AAI07151 Q3KNR4
DQ442656 ABD97848 Q1W386
EU446646 ABZ92175  
AB008913 BAA24506 O43316

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAX4 NP_006184 R.norvegicus Pax4 83630   NP_113987 80
M.musculus Pax4 18506 Gene Info NP_035168 79

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)