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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF4A1, Eukaryotic translation initiation factor 4A1
Sequence ID:NM_001416
NM_001204510
Entrez Gene ID:1973
Ensembl ID:ENSG00000161960

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 7476143 - 7481941


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4096621Full LengthBC009585eukaryotic translation initiation factor 4A, isoform 1
6371531Full LengthBC073752eukaryotic translation initiation factor 4A, isoform 1
2821876IncompleteBC006210eukaryotic translation initiation factor 4A, isoform 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001407  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001204510 NP_001191439      
NM_001416 NP_001407 P60842 EC 3.6.4.13 DEAD
Helicase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC009585 AAH09585 P60842 EC 3.6.4.13
BC073752 AAH73752 P60842 EC 3.6.4.13
BT019880 AAV38683 P60842 EC 3.6.4.13
BT019881 AAV38684 P60842 EC 3.6.4.13
DQ893044 ABM83970    
DQ896288 ABM87287    
D13748 BAA02897 P60842 EC 3.6.4.13
AK289453 BAF82142 A8K088  
AK291971 BAF84660 A8K7F6  
AK312630 BAG35515 P60842 EC 3.6.4.13
AK296664 BAG59261 B4DKP9  
AK297916 BAG60234 B4DNH2  
AK303222 BAG64309 B4E047  
AK303599 BAG64614 B4E102  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF4A1 NP_001407 M.musculus Eif4a1 13681 Gene Info NP_659207 100
R.norvegicus Eif4a1 287436   NP_955404 100
N.crassa NCU07420 3874573   XP_958421 79
S.pombe SPAC1006.07 2542948   NP_594854 76
A.thaliana AT1G72730 843605   NP_177417 71
S.cerevisiae TIF2 853303   NP_012397 67
S.cerevisiae TIF1 853933   NP_012985 67

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta