Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SYNE1, spectrin repeat containing, nuclear envelope 1
Sequence ID:NM_033071
NM_182961
NM_001099267
NM_001134379
NM_015293
NM_133650
RefSeqGene ID:NG_012855
Entrez Gene ID:23345
Ensembl ID:ENSG00000131018

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
EMERY-DREIFUSS MUSCULAR DYSTROPHY 4, AUTOSOMAL DOMINANT 
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 8 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 152442914 - 152553351

 Exon Info From UCSC:
NM_033071
NM_182961
NM_015293
NM_133650

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3077391IncompleteBC090927spectrin repeat containing, nuclear envelope 1
4830497IncompleteBC039121spectrin repeat containing, nuclear envelope 1
8860128IncompleteBC150289spectrin repeat containing, nuclear envelope 1

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_033071 NP_149062    
NM_182961 NP_892006 Q8NF91  

Related Sequences

 
mRNAGenPeptSwissProt
AF043290 AAC02992 Q8NF91
BC039121 AAH39121 Q3ZCV0
BC090927 AAH90927 Q5BKU8
BC150289 AAI50290 A7E2D5
AY061755 AAL33798 Q8NF91
AY061756 AAL33799 Q8NF91
AF444779 AAL38031 Q8NF91
AY135172 AAM95335 Q8NF91
AF535142 AAN03486 Q8NF91
AF495910 AAN60442 Q8NF91
AY183142 AAO23669 Q8NF91
AY184203 AAO27771 Q8NF91
AY184206 AAO27774 Q8NF91
JQ740783 AFN44378 I6XKI8
JQ740784 AFN44379 I6WZ08
JQ740785 AFN44380 I6XXQ1
JQ740786 AFN44381 I6WNA2
JQ754364 AFN44382 I6XTI3
JQ754366 AFN44384 I6WZ14
AB018339 BAA34516 Q8NF91
AB033088 BAA86576 Q8NF91
AB051543 BAB21847 Q8NF91
AK056122 BAB71097 Q8NF91
AK094094 BAC04284 Q8NF91
AK122691 BAG53670 B3KV58
AK304825 BAG65573 B4E3R1
AK316101 BAH14472 B7Z9Y6
AL713682 CAD28486 Q8NF91
BX537517 CAD97770 Q7Z3R1
BX537837 CAD97849 Q7Z3K4
CR933676 CAI45971 Q5H9Q3
FM162565 CAQ57272 B3W695
BK000543 DAA01060 Q7RTM4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SYNE1 NP_892006 M.musculus Syne1 64009 Gene Info NP_001073154 88
R.norvegicus Syne1 499010   NP_001025080 85
C.elegans anc-1 172034   NP_491353 23
D.melanogaster Msp-300 3771968   NP_001188697 21
A.gambiae AgaP_AGAP009554 1271352   XP_310129 21

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)