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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ACTA1, actin, alpha 1, skeletal muscle
Sequence ID:NM_001100
RefSeqGene ID:NG_006672
Entrez Gene ID:58
Ensembl ID:ENSG00000143632

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MYOPATHY, ACTIN, CONGENITAL,WITH EXCESS OF THIN MYOFILAMENTS 
MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION 1SEPN1
TPM3
TPM3
TPM3

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 229566996 - 229569841

NM_001100 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
20414229566994229567388
415596229567467229567648
597788229567740229567931
789950229568016229568177
9511275229568302229568626
12761416229568733229568873
14171509229569750229569842

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4291656Full LengthBC012597actin, alpha 1, skeletal muscle

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001091  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001100 NP_001091 P68133 Actin

Related Sequences

 
mRNAGenPeptSwissProt
J00068 AAB59376 P68133
BC012597 AAH12597 P68133
AY280960 AAP37280 Q7Z7J6
DQ892949 ABM83875  
DQ896197 ABM87196  
AK096902 BAG53395 B3KUD3
AK300697 BAH13327 B7Z6P1
CR536516 CAG38754 P68133
CR541796 CAG46595 P68133

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACTA1 NP_001091 M.musculus Acta1 11459 Gene Info NP_033736 100
R.norvegicus Acta1 29437   NP_062085 100

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta