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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSC, cathepsin C
Sequence ID:NM_001114173
NM_001814
NM_148170
RefSeqGene ID:NG_007952
Entrez Gene ID:1075
Ensembl ID:ENSG00000109861

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HAIM-MUNK SYNDROME 
PAPILLON-LEFEVRE SYNDROME 
PERIODONTITIS, JUVENILE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q14.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 88027123 - 88070866

 Exon Info From UCSC:
NM_001114173
NM_001814
NM_148170

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2967491IncompleteBC008059cathepsin C
3503348IncompleteBC023559cathepsin C
100002235BC146692cathepsin C

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001805  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001114173 NP_001107645      
NM_001814 NP_001805 P53634 EC 3.4.14.1 Peptidase_C1
NM_148170 NP_680475      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC054028 AAH54028 P53634 EC 3.4.14.1
BC100891 AAI00892 P53634 EC 3.4.14.1
BC100892 AAI00893 P53634 EC 3.4.14.1
BC100893 AAI00894 P53634 EC 3.4.14.1
BC100894 AAI00895 P53634 EC 3.4.14.1
BC109386 AAI09387 P53634 EC 3.4.14.1
BC110071 AAI10072 P53634 EC 3.4.14.1
BC113850 AAI13851 P53634 EC 3.4.14.1
BC113897 AAI13898 P53634 EC 3.4.14.1
BC146692 AAI46693    
AF234263 AAL48191 P53634 EC 3.4.14.1
AF234264 AAL48192 P53634 EC 3.4.14.1
AF254757 AAL48195 P53634 EC 3.4.14.1
AF525032 AAQ08887 P53634 EC 3.4.14.1
AF525033 AAQ08888 P53634 EC 3.4.14.1
AK223038 BAD96758 P53634 EC 3.4.14.1
AK292117 BAF84806 P53634 EC 3.4.14.1
AK311923 BAG34864 P53634 EC 3.4.14.1
AK296190 BAG58920 B4DJQ8  
X87212 CAA60671 P53634 EC 3.4.14.1
BX537913 CAD97897 P53634 EC 3.4.14.1
AM393622 CAL38498    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSC NP_001805 R.norvegicus Ctsc 25423   NP_058793 79
M.musculus Ctsc 13032 Gene Info NP_034112 78
P.falciparum PF11_0174 810721   XP_001347845 41
P.falciparum PFL2290w 811510   XP_001350862 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)