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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CRB1, crumbs homolog 1 (Drosophila)
Sequence ID:NM_001193640
NM_001257965
NM_001257966
NM_201253
NR_047563
NR_047564
NM_012076
RefSeqGene ID:NG_008483
Entrez Gene ID:23418
Ensembl ID:ENSG00000134376

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEBER CONGENITAL AMAUROSIS 8 
PIGMENTED PARAVENOUS CHORIORETINAL ATROPHY 
RETINITIS PIGMENTOSA-12, AUTOSOMAL RECESSIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q31-q32.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 197237405 - 197327258

 Exon Info From UCSC:
NM_001193640
NM_201253

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020258Full LengthBC136271crumbs homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_957705  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001193640 NP_001180569    
NM_001257965 NP_001244894    
NM_001257966 NP_001244895    
NM_201253 NP_957705 P82279 EGF
Laminin_G_2

Related Sequences

 
mRNAGenPeptSwissProt
AF154671 AAF01361 P82279
BC136271 AAI36272 P82279
AY043323 AAL10680 P82279
AY043324 AAL10681 P82279
AY043325 AAL10682 P82279
AB208923 BAD92160 Q59H36
AK289733 BAF82422 A8K118
AK299367 BAH13017 B7Z5T1
AK299368 BAH13018 B7Z5T2
AK302818 BAH13810 B7Z824
AK302826 BAH13812 B7Z826
BX640729 CAE45845 P82279
AJ748821 CAG38658 P82279

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CRB1 NP_957705 M.musculus Crb1 170788 Gene Info NP_573502 76
R.norvegicus Crb1 304825   NP_001100652 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)