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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAPK10, mitogen-activated protein kinase 10
Sequence ID:NM_002753
NM_138980
NM_138981
NM_138982
RefSeqGene ID:NG_013325
Entrez Gene ID:5602
Ensembl ID:ENSG00000109339

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPTIC ENCEPHALOPATHY, LENNOX-GASTAUT TYPE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q22.1-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 86937632 - 87028806

 Exon Info From UCSC:
NM_002753
NM_138980
NM_138981
NM_138982

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4838495Full LengthBC051731mitogen-activated protein kinase 10
5261221Full LengthBC035057mitogen-activated protein kinase 10
5721954Full LengthBC065516mitogen-activated protein kinase 10
4792970IncompleteBC022492mitogen-activated protein kinase 10

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_620448  NP_620446  NP_002744  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002753 NP_002744     Pkinase
Pkinase_Tyr
NM_138980 NP_620446     Pkinase
Pkinase_Tyr
NM_138981 NP_620447      
NM_138982 NP_620448 P53779 EC 2.7.11.24 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U07620 AAC50101 P53779 EC 2.7.11.24
U34819 AAC50604 P53779 EC 2.7.11.24
U34820 AAC50605 P53779 EC 2.7.11.24
BC035057 AAH35057 P53779 EC 2.7.11.24
BC051731 AAH51731 Q499Y8  
BC065516 AAH65516 A8MWW6  
AK057723 BAG51956 P53779 EC 2.7.11.24
AK091104 BAG52284 B3KR72  
AK124791 BAG54096 P53779 EC 2.7.11.24
AK294125 BAH11677 B7Z1Z1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAPK10 NP_620448 R.norvegicus Mapk10 25272   NP_036938 100
M.musculus Mapk10 26414 Gene Info NP_001075036 100

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta