Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KCNE1, potassium voltage-gated channel, Isk-related family, member 1
Sequence ID:NM_000219
NM_001127668
NM_001127669
NM_001127670
NM_001270402
NM_001270403
NM_001270404
NM_001270405
RefSeqGene ID:NG_009091
Entrez Gene ID:3753
Ensembl ID:ENSG00000180509

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
JERVELL AND LANGE-NIELSEN SYNDROMEKCNQ1
JERVELL AND LANGE-NIELSEN SYNDROME 2 
LONG QT SYNDROME-5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 35820757 - 35883571

 Exon Info From UCSC:
NM_000219
NM_001127668
NM_001127669
NM_001127670

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5266786Full LengthBC036452potassium voltage-gated channel, Isk-related family, member 1
6198685Full LengthBC046224potassium voltage-gated channel, Isk-related family, member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000210  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000219 NP_000210 P15382 ISK_Channel
NM_001127668 NP_001121140    
NM_001127669 NP_001121141    
NM_001127670 NP_001121142    
NM_001270402 NP_001257331    
NM_001270403 NP_001257332    
NM_001270404 NP_001257333    
NM_001270405 NP_001257334    

Related Sequences

 
mRNAGenPeptSwissProt
L28168 AAA58418 P15382
Q6FHJ6
AF135188 AAD25096 P15382
BC036452 AAH36452 P15382
BC046224 AAH46224 Q6FHJ6
AY789479 AAX11417 Q5DI96
AY789480 AAX11418 Q5DI96
EU008568 ABS31132 A7LFK2
EU008569 ABS31133 A7LFK2
EU008570 ABS31134 A7LFK4
EF514882 ABS84250 C7S316
EF514883 ABS84251 Q6FHJ6
JF432567 ADZ15784  
AK313543 BAG36319 Q6FHJ6
AK304336 BAG65181 B4E2L9
CR541756 CAG46556 Q6FHJ6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KCNE1 NP_000210 R.norvegicus Kcne1 25471   NP_037105 78
M.musculus Kcne1 16509 Gene Info NP_032450 77

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)