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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GLRA1, glycine receptor, alpha 1
Sequence ID:NM_000171
NM_001146040
RefSeqGene ID:NG_011764
Entrez Gene ID:2741
Ensembl ID:ENSG00000145888

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPEREKPLEXIA, HEREDITARY 1, AUTOSOMAL DOMINANT OR RECESSIVEGLRB
GPHN
SLC6A5

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 151229251 - 151304393

 Exon Info From UCSC:
NM_000171
NM_001146040

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915298Full LengthBC074980glycine receptor, alpha 1
40084102Full LengthBC114947glycine receptor, alpha 1
40084103Full LengthBC114967glycine receptor, alpha 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000162  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000171 NP_000162 P23415 Neur_chan_LBD
Neur_chan_memb
NM_001146040 NP_001139512 P23415  

Related Sequences

 
mRNAGenPeptSwissProt
BC074980 AAH74980 P23415
BC114947 AAI14948 P23415
BC114967 AAI14968 Q14C71
AK312702 BAG35580 P23415
X52009 CAA36258 P23415

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GLRA1 NP_001139512 M.musculus Glra1 14654 Gene Info NP_065238 99
R.norvegicus Glra1 25674   NP_037265 98
C.elegans glc-3 178930   NP_504441 44
C.elegans avr-14 172270   NP_001020963 43
C.elegans avr-15 179834   NP_001024076 43
D.melanogaster GluClalpha 42350   NP_001014641 43
C.elegans glc-1 180086   NP_507090 42
A.gambiae AgaP_AGAP001434 4577187   XP_321696 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)