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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TUFM, Tu translation elongation factor, mitochondrial
Sequence ID:NM_003321
RefSeqGene ID:NG_008964
Entrez Gene ID:7284
Ensembl ID:ENSG00000178952

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 28854107 - 28857635

NM_003321 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
197562885373128854468
7578762885505628855175
87710282885527028855421
102911332885555028855654
113412662885573928855871
126714312885601828856182
143215362885627128856375
153717032885663428856800
170418982885723228857426
189920892885753828857728

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3536952Full LengthBC001633Tu translation elongation factor, mitochondrial
3629164Full LengthBC010041Tu translation elongation factor, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003312  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003321 NP_003312   GTP_EFTU
GTP_EFTU_D3
GTP_EFTU_D2

Related Sequences

 
mRNAGenPeptSwissProt
L38995 AAB00499 P49411
S75463 AAC60647 P49411
BC001633 AAH01633 P49411
BC010041 AAH10041 P49411
HQ448224 ADQ32704  
X84694 CAA59169 P49411

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TUFM NP_003312 M.musculus Tufm 233870 Gene Info NP_766333 94
R.norvegicus Tufm 293481   NP_001099765 94
A.gambiae AgaP_AGAP006996 1270103   XP_308774 67
D.melanogaster EfTuM 44438   NP_001163144 63
S.cerevisiae TUF1 854359   NP_014830 63
C.elegans tufm-1 175398   NP_497623 57
A.thaliana AT4G02930 828134   NP_192202 57
N.crassa NCU03737 3877588   XP_961513 57
S.pombe tuf1 2540210   NP_595746 56
P.falciparum MAL13P1.164 813717   XP_001350039 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)