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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CACNB4, calcium channel, voltage-dependent, beta 4 subunit
Sequence ID:NM_000726
NM_001005746
NM_001005747
NM_001145798
RefSeqGene ID:NG_012641
Entrez Gene ID:785
Ensembl ID:ENSG00000182389

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, IDIOPATHIC GENERALIZEDME2
EPILEPSY, IDIOPATHIC GENERALIZEDCLCN2
EPISODIC ATAXIA, TYPE 5 
MYOCLONIC EPILEPSY, JUVENILECLCN2
EFHC1
GABRA1

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 152695632 - 152955537

 Exon Info From UCSC:
NM_000726
NM_001005746
NM_001005747
NM_001145798

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915578Full LengthBC075049calcium channel, voltage-dependent, beta 4 subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001005746  NP_000717  NP_001005747  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000726 NP_000717 O00305 Ca_channel_B
NM_001005746 NP_001005746   Ca_channel_B
NM_001005747 NP_001005747   Ca_channel_B
NM_001145798 NP_001139270    

Related Sequences

 
mRNAGenPeptSwissProt
U95020 AAB53333 O00305
AF038852 AAC24206 O00305
BC075049 AAH75049 O00305
AY054985 AAL14351 O00305
HQ214056 ADP09414 E7DBM8
AB302276 BAF73808 O00305
AK290049 BAF82738 O00305
AK291378 BAF84067 A8K5R3
AK294398 BAG57651 O00305
AK316045 BAH14416 O00305

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CACNB4 NP_000717 M.musculus Cacnb4 12298 Gene Info NP_001032176 99
R.norvegicus Cacnb4 58942   NP_001099203 99
D.melanogaster Ca-beta 34557   NP_995684 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)