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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CDK6, cyclin-dependent kinase 6
Sequence ID:NM_001145306
NM_001259
RefSeqGene ID:NG_015888
Entrez Gene ID:1021
Ensembl ID:ENSG00000105810

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 92235961 - 92237851

 Exon Info From UCSC:
NM_001145306
NM_001259

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6377987Full LengthBC052264cyclin-dependent kinase 6
4538214IncompleteBC012914cyclin-dependent kinase 6
4995539IncompleteBC027989cyclin-dependent kinase 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001250  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001145306 NP_001138778      
NM_001259 NP_001250 Q00534 EC 2.7.11.22 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC052264 AAH52264 Q00534 EC 2.7.11.22
AK313491 BAG36273 A4D1G0  
X66365 CAA47008 Q00534 EC 2.7.11.22

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDK6 NP_001250 R.norvegicus Cdk6 114483   XP_342639 97
M.musculus Cdk6 12571 Gene Info NP_034003 96
A.gambiae AgaP_AGAP005817 1276486   XP_315841 52
D.melanogaster Cdk4 36854   NP_477196 47
C.elegans cdk-4 181472   NP_510256 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta