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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. AP2S1, adaptor-related protein complex 2, sigma 1 subunit
Sequence ID:NM_004069
Entrez Gene ID:1175
Ensembl ID:ENSG00000042753

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.2-q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 47341703 - 47349400

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4304127Full LengthBC006337adaptor-related protein complex 2, sigma 1 subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004060  NP_067586  

Protein Infomation

NM_004069 NP_004060 P53680 Clat_adaptor_s
NM_021575 NP_067586   Clat_adaptor_s

Related Sequences

BC006337 AAH06337 P53680
JF432568 ADZ15785  
AK312003 BAG34941 P53680
AJ010148 CAA09018 P53680
AJ010149 CAA09019 P53680
X97074 CAA65782 P53680

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AP2S1 NP_004060 R.norvegicus Ap2s1 65046   NP_075241 100
M.musculus Ap2s1 232910 Gene Info NP_941015 100
A.gambiae AgaP_AGAP001703 1281473   XP_321389 96
D.melanogaster AP-2sigma 42525   NP_650961 96
C.elegans aps-2 184091   NP_508767 95
N.crassa NCU07989 3878798   XP_962659 68
A.thaliana AT1G47830 841199   NP_175219 61
S.pombe aps2 2541086   NP_596138 57
S.cerevisiae APS2 853521   NP_012592 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)