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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DNASE2, deoxyribonuclease II, lysosomal
Sequence ID:NM_001375
Entrez Gene ID:1777
Ensembl ID:ENSG00000105612

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 12986364 - 12992261

NM_001375 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
411561298602412987176
115713541298919512989392
135515191298948312989647
152015981299161512991693
159917791299178512991965
178020111299210312992334

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3528108Full LengthBC010419deoxyribonuclease II, lysosomal
5502061Full LengthBC065209deoxyribonuclease II, lysosomal

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001366  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001375 NP_001366 O00115 EC 3.1.22.1 DNase_II

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF045937 AAC35751 O00115 EC 3.1.22.1
AF060222 AAC39852 O00115 EC 3.1.22.1
AF047016 AAC77366 O00115 EC 3.1.22.1
BC010419 AAH10419 O00115 EC 3.1.22.1
BC065209 AAH65209 O00115 EC 3.1.22.1
BT007047 AAP35696 O00115 EC 3.1.22.1
FJ752529 ACN63522 C0LQF2  
AB004574 BAA28623 O00115 EC 3.1.22.1
AK315358 BAG37753 O00115 EC 3.1.22.1
AK075449 BAG52141 B3KQS9  
AK297493 BAH12592 B7Z4K6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DNASE2 NP_001366 M.musculus Dnase2a 13423 Gene Info NP_034192 73
R.norvegicus Dnase2a 171575   NP_612548 73
A.gambiae AgaP_AGAP003295 1279761   XP_319521 36
C.elegans nuc-1 181174   NP_509604 36
C.elegans tag-198 176166   NP_498817 36
D.melanogaster DNaseII 48228   NP_650672 35
C.elegans crn-6 176316   NP_499062 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)