Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FGD4, FYVE, RhoGEF and PH domain containing 4
Sequence ID:NM_139241
RefSeqGene ID:NG_008626
Entrez Gene ID:121512
Ensembl ID:ENSG00000139132

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, TYPE 4H 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 32655093 - 32793673

 Exon Info From UCSC:
NM_139241

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4831180Full LengthBC045552FYVE, RhoGEF and PH domain containing 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_640334  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_139241 NP_640334 Q96M96 PH
RhoGEF
FYVE

Related Sequences

 
mRNAGenPeptSwissProt
BC045552 AAH45552 Q49A55
AY367054 AAQ72372 Q96M96
AK057294 BAB71413 Q96M96
AK297025 BAH12479 B7Z493
AK303334 BAH13945 B7Z8F9
AL713762 CAD28532 Q96M96

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FGD4 NP_640334 M.musculus Fgd4 224014 Gene Info NP_631978 84
R.norvegicus Fgd4 246174   NP_640356 83

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)