Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. OTC, ornithine carbamoyltransferase
Sequence ID:NM_000531
RefSeqGene ID:NG_008471
Entrez Gene ID:5009
Ensembl ID:ENSG00000036473

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ORNITHINE TRANSCARBAMYLASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 38211780 - 38280489

NM_000531 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12913821173538212025
2924303822654338226681
4315123822904838229129
5136003824059438240681
6017543826052738260680
7558773826287038262992
8789313826799438268047
93210813826812838268277
108212193827111438271251
122016463828027538280701

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915205Full LengthBC074745ornithine carbamoyltransferase
40032502Full LengthBC107153ornithine carbamoyltransferase
40032511Full LengthBC107154ornithine carbamoyltransferase
40083569Full LengthBC114496ornithine carbamoyltransferase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000522  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000531 NP_000522 P00480 EC 2.1.3.3 OTCace
OTCace_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
K02100 AAA59975 P00480 EC 2.1.3.3
BC074745 AAH74745 P00480 EC 2.1.3.3
BC107153 AAI07154 P00480 EC 2.1.3.3
BC107154 AAI07155 P00480 EC 2.1.3.3
BC114496 AAI14497 P00480 EC 2.1.3.3
AK292757 BAF85446 P00480 EC 2.1.3.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens OTC NP_000522 M.musculus Otc 18416 Gene Info NP_032795 93
R.norvegicus Otc 25611   NP_037210 92
N.crassa NCU01667 3873060   XP_956873 52
S.pombe arg3 2543593   NP_593692 48
A.thaliana OTC 843869   NP_177667 44
S.cerevisiae ARG3 853357   NP_012447 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)