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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AKR1B10, aldo-keto reductase family 1, member B10 (aldose reductase)
Sequence ID:NM_020299
Entrez Gene ID:57016
Ensembl ID:ENSG00000198074

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 134222364 - 134226156

NM_020299 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1386134212343134212728
387554134215394134215561
555671134216659134216775
672749134217755134217832
750872134221401134221523
873979134221802134221908
9801061134222331134222412
10621145134222945134223028
11461228134223686134223768
12291595134225798134226164

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3639480Full LengthBC008837aldo-keto reductase family 1, member B10 (aldose reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_064695  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_020299 NP_064695 O60218 Aldo_ket_red

Related Sequences

 
mRNAGenPeptSwissProt
AF044961 AAC15671 O60218
U37100 AAC17469 O60218
AF052577 AAC36465 O60218
BC008837 AAH08837 O60218
AF524864 AAO13380 O60218
BT006794 AAP35440 O60218
DQ890678 ABM81604  
EU176471 ABW03272  
CR541801 CAG46600 O60218

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKR1B10 NP_064695 M.musculus Akr1b8 14187 Gene Info NP_032038 82
R.norvegicus Akr1b8 286921   NP_775159 82
S.cerevisiae YPR1 851974   NP_010656 46
S.cerevisiae GCY1 854287   NP_014763 45
A.thaliana AT2G21250 816664   NP_179721 44
A.thaliana AT2G21260 816665   NP_179722 43
N.crassa NCU01906 3881683   XP_965537 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)