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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. HNF4A, hepatocyte nuclear factor 4, alpha
Sequence ID:NM_000457
NM_001030003
NM_001030004
NM_001258355
NM_175914
NM_178849
NM_178850
RefSeqGene ID:NG_009818
Entrez Gene ID:3172
Ensembl ID:ENSG00000101076

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
MODY, TYPE IINS

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 43030039 - 43058305

 Exon Info From UCSC:
NM_000457
NM_001030003
NM_001030004
NM_175914
NM_178849
NM_178850

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021539Full LengthBC137539hepatocyte nuclear factor 4, alpha
9021540Full LengthBC137540hepatocyte nuclear factor 4, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_849180  NP_787110  NP_001025175  NP_000448  NP_001025174  NP_849181  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000457 NP_000448 P41235 Hormone_recep
zf-C4
NM_001030003 NP_001025174   Hormone_recep
zf-C4
NM_001030004 NP_001025175   Hormone_recep
zf-C4
NM_001258355 NP_001245284    
NM_175914 NP_787110   Hormone_recep
zf-C4
NM_178849 NP_849180   Hormone_recep
zf-C4
NM_178850 NP_849181   Hormone_recep
zf-C4

Related Sequences

 
mRNAGenPeptSwissProt
BC137539 AAI37540 P41235
BC137540 AAI37541 P41235
AY680696 AAT91237 P41235
AY680697 AAT91238 P41235
AY680698 AAT91239 P41235
FJ608822 ACM50922 B9VVT8
HQ692860 ADZ17371 F1D8S2
HQ692868 ADZ17379 F1D8T0
HQ692869 ADZ17380 F1D8T1
AB307703 BAH02294 B6ZGT3
X76930 CAA54248 P41235
X87870 CAA61133 P41235
X87871 CAA61134 P41235
X87872 CAA61135 P41235
Z49825 CAA89989 P41235

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HNF4A NP_000448 R.norvegicus Hnf4a 25735   NP_071516 96
M.musculus Hnf4a 15378 Gene Info NP_032287 96
C.elegans nhr-69 172840   NP_492615 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)