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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. VAV1, vav 1 guanine nucleotide exchange factor
Sequence ID:NM_001258206
NM_001258207
NM_005428
Entrez Gene ID:7409
Ensembl ID:ENSG00000141968

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 6772724 - 6857377


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3842829Full LengthBC013361vav 1 guanine nucleotide exchange factor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005419  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001258206 NP_001245135    
NM_001258207 NP_001245136    
NM_005428 NP_005419 P15498 SH2
SH3_1
C1_1
PH
CH
RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
BC013361 AAH13361 Q96D37
AK313307 BAG36112 B2R8B5
AK301128 BAG62721 B4DVK9
X16316 CAA34383 P15498
X83931 CAA58783 P15498

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens VAV1 NP_005419 M.musculus Vav1 22324 Gene Info NP_035821 93
R.norvegicus Vav1 25156   NP_036891 93
D.melanogaster vav 32920   NP_728235 37
A.gambiae AgaP_AGAP010292 1279719   XP_319489 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta