Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPARC, secreted protein, acidic, cysteine-rich (osteonectin)
Sequence ID:NM_003118
Entrez Gene ID:6678
Ensembl ID:ENSG00000113140

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31.3-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 151042003 - 151066494

NM_003118 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2906092Full LengthBC004974secreted protein, acidic, cysteine-rich (osteonectin)
3529445Full LengthBC008011secreted protein, acidic, cysteine-rich (osteonectin)
6186685Full LengthBC072457secreted protein, acidic, cysteine-rich (osteonectin)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003109  

Protein Infomation

NM_003118 NP_003109 P09486 Kazal_1

Related Sequences

J03040 AAA60570 P09486
BC004974 AAH04974 P09486
BC008011 AAH08011 P09486
BC072457 AAH72457 P09486
AY545555 AAS50152 Q6QE20
DQ893415 ABM84341  
DQ896734 ABM87733  
D28381 BAA05747  
AK315591 BAG37963 B2RDL6
AK299441 BAG61416 B4DRV4
Y00755 CAA68724 P09486
CR456799 CAG33080 P09486

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPARC NP_003109 M.musculus Sparc 20692 Gene Info NP_033268 93
R.norvegicus Sparc 24791   NP_036788 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)