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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPCS1, signal peptidase complex subunit 1 homolog (S. cerevisiae)
Sequence ID:NM_014041
Entrez Gene ID:28972
Ensembl ID:ENSG00000114902

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 52740125 - 52742182

NM_014041 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3462307Full LengthBC000884signal peptidase complex subunit 1 homolog (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_054760  

Protein Infomation

NM_014041 NP_054760 Q9Y6A9 SPC12

Related Sequences

AF092138 AAD40380 Q9Y6A9
BC000884 AAH00884 Q9Y6A9
L38852 AAL31361 Q9Y6A9
AK027426 BAG51320 Q9Y6A9
AX775783 CAE11591 Q9Y6A9
AX775785 CAE11592  
AX775787 CAE11593  
AX775833 CAE11616 Q9Y6A9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPCS1 NP_054760 R.norvegicus Spcs1 290555   NP_001124478 95
M.musculus Spcs1 69019 Gene Info NP_081187 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)