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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. E2F4, E2F transcription factor 4, p107/p130-binding
Sequence ID:NM_001950
Entrez Gene ID:1874
Ensembl ID:ENSG00000205250

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 67226130 - 67232024

NM_001950 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11986722606767226264
1993086722666367226772
3094706722691167227072
4715146722737467227417
5155766722830067228361
5778716722858867228882
87210966722968467229908
109711446723150167231548
114511896723176967231813
119020996723191067232819

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4585569Full LengthBC033180E2F transcription factor 4, p107/p130-binding

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001941  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001950 NP_001941 Q16254 E2F_TDP

Related Sequences

 
mRNAGenPeptSwissProt
S75174 AAB32597 Q16254
U15641 AAC50119 Q16254
BC033180 AAH33180 Q16254
DQ892803 ABM83729  
AB451292 BAG70106 Q16254
AB451425 BAG70239 Q16254
X86096 CAA60050 Q16254

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens E2F4 NP_001941 M.musculus E2f4 104394 Gene Info NP_683754 93
R.norvegicus LOC100360427 100360427   XP_002728642 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta