Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POLE3, polymerase (DNA directed), epsilon 3, accessory subunit
Sequence ID:NM_017443
NR_027261
Entrez Gene ID:54107
Ensembl ID:ENSG00000148229

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:9q33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 116169517 - 116171103

NM_017443 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
241769116169517116171262
17701888116171889116172007
18891974116172334116172419
19752155116172507116172687
21562288116172896116173028

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822216Full LengthBC003166polymerase (DNA directed), epsilon 3 (p17 subunit)
2822216Full LengthBC004170polymerase (DNA directed), epsilon 3 (p17 subunit)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_059139  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_017443 NP_059139   CBFD_NFYB_HMF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF226077 AAF72417 Q9NRF9 EC 2.7.7.7
BC003166 AAH03166 Q9NRF9 EC 2.7.7.7
BC004170 AAH04170 Q9NRF9 EC 2.7.7.7
AY720898 AAU15052 Q9NRF9 EC 2.7.7.7
JF432738 ADZ15955    
AK074629 BAC11099 Q9NRF9 EC 2.7.7.7
AK074762 BAC11190 Q9NRF9 EC 2.7.7.7
AK074782 BAC11206 Q9NRF9 EC 2.7.7.7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLE3 NP_059139 R.norvegicus Pole3 298098   NP_001007653 97
R.norvegicus LOC100362333 100362333   XP_002729875 97
M.musculus Pole3 59001 Gene Info NP_067473 94
A.gambiae AgaP_AGAP012825 1267591   XP_306148 51
A.gambiae AgaP_AGAP005051 1274732   XP_313924 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)