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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CHRNA4, cholinergic receptor, nicotinic, alpha 4 (neuronal)
Sequence ID:NM_000744
NM_001256573
NR_046317
RefSeqGene ID:NG_011931
Entrez Gene ID:1137
Ensembl ID:ENSG00000101204

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, NOCTURNAL FRONTAL LOBE, 1 
NICOTINE ADDICTION, PROTECTIONFROMCYP2A6
GABBR2
SLC6A3

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.2-q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 61977520 - 61981264

Transcript StartTranscript EndChromosomal Start Chromosomal End
135516197466461978214
355249266198100461982378
492750366198732661987435
503750816198772261987766
508252336199089961991050
523454876199244161992694

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40007296Full LengthBC096290cholinergic receptor, nicotinic, alpha 4
40007297Full LengthBC096291cholinergic receptor, nicotinic, alpha 4
40007298Full LengthBC096292cholinergic receptor, nicotinic, alpha 4
40007299Full LengthBC096293cholinergic receptor, nicotinic, alpha 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000735  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000744 NP_000735 P43681 Neur_chan_LBD
Neur_chan_memb
NM_001256573 NP_001243502    

Related Sequences

 
mRNAGenPeptSwissProt
L35901 AAA64743 P43681
U62433 AAB40111 P43681
BC096290 AAH96290 P43681
BC096291 AAH96291 Q4VAQ5
BC096292 AAH96292 Q4VAQ3
BC096293 AAH96293 Q4VAQ3
AK296430 BAG59090 B4DK78
X87629 CAA60959 P43681
X89746
X89745
X89743
X89741
X89744
X89742
CAA61893 P43681
Y08421 CAA69698 P43681

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHRNA4 NP_000735 M.musculus Chrna4 11438 Gene Info NP_056545 85
R.norvegicus Chrna4 25590   NP_077330 85
D.melanogaster nAcRbeta-64B 38545   NP_523927 53
A.gambiae AgaP_AGAP000966 1270461   XP_309158 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)