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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NSD1, nuclear receptor binding SET domain protein 1
Sequence ID:NM_022455
NM_172349
RefSeqGene ID:NG_009821
Entrez Gene ID:64324
Ensembl ID:ENSG00000165671

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
BECKWITH-WIEDEMANN SYNDROMECDKN1C
H19
KCNQ1OT1
KCNQ1OT1
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NUP214
PICALM
RUNX1
RUNX1
SH3GL1
TERT
WHSC1L1
SOTOS SYNDROME 1 
WEAVER SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 176722129 - 176722758

 Exon Info From UCSC:
NM_022455
NM_172349

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9056998Full LengthBC150628nuclear receptor binding SET domain protein 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_758859  NP_071900  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_022455 NP_071900 Q96L73 EC 2.1.1.43 PHD
PWWP
SET
NM_172349 NP_758859     PHD
PWWP
SET

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC021961 AAH21961 Q6PJ64  
BC139789 AAI39790 A4QPE5  
BC150628 AAI50629 B2RWP5  
AF322907 AAK92049 Q96L73 EC 2.1.1.43
AY049721 AAL06645 Q96L73 EC 2.1.1.43
AF380302 AAL27991 Q96L73 EC 2.1.1.43
AF395588 AAL40694 Q96L73 EC 2.1.1.43
AK025916 BAB15281 Q9H6H8  
AK026066 BAB15346 Q9H6B5  
AK055187 BAB70868 Q96DQ7  
AK056667 BAB71247 Q96MN8  
AK091358 BAC03645 Q8NB95  
AL832983 CAH56331 Q658U6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NSD1 NP_071900 M.musculus Nsd1 18193 Gene Info NP_032765 84
R.norvegicus Nsd1 306764   NP_001100807 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)