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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. BAP1, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Sequence ID:NM_004656
RefSeqGene ID:NG_031859
Entrez Gene ID:8314
Ensembl ID:ENSG00000163930

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
TUMOR PREDISPOSITION SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.31-p21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 52435688 - 52436177

 Exon Info From UCSC:
NM_004656

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3543914Full LengthBC001596BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004647  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004656 NP_004647 Q92560 EC 3.4.19.12 Peptidase_C12

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF045581 AAC15970 Q92560 EC 3.4.19.12
BC001596 AAH01596 Q92560 EC 3.4.19.12
AY130008 AAN05092 Q92560 EC 3.4.19.12
DQ892545 ABM83471    
DQ895756 ABM86682    
D87462 BAA13401 Q92560 EC 3.4.19.12
D88812 BAB46921 Q92560 EC 3.4.19.12
AB002534 BAB46926 Q96TC6  
AK292608 BAF85297 Q92560 EC 3.4.19.12
AK092725 BAG52602 B3KS40  
AK295395 BAG58349 B4DI37  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens BAP1 NP_004647 M.musculus Bap1 104416 Gene Info NP_081364 94
R.norvegicus Bap1 306257   NP_001100762 94
D.melanogaster calypso 36794   NP_788374 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)