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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DEFB4A, defensin, beta 4A
Sequence ID:NM_004942
RefSeqGene ID:NG_023301
Entrez Gene ID:1673
Ensembl ID:ENSG00000171711

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CROHN DISEASE-ASSOCIATED GROWTH FAILUREDLG5
IL23R
IL6
NOD2
SLC22A4

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 7752198 - 7754182

NM_004942 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
19477521987752291
9533577539957754235

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262691Full LengthBC069285defensin, beta 4
7939828Full LengthBC093983defensin, beta 4
7939830Full LengthBC093985defensin, beta 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004933  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004942 NP_004933 O15263 Defensin_beta

Related Sequences

 
mRNAGenPeptSwissProt
BC069285 AAH69285 O15263
BC093983 AAH93983 O15263
BC093985 AAH93985 O15263
Z71389 CAA95992 O15263

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DEFB4A NP_004933 H.sapiens DEFB4B 100289462 Gene Info NP_001192195 100

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)