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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. RPS6KA4, ribosomal protein S6 kinase, 90kDa, polypeptide 4
Sequence ID:NM_001006944
NM_003942
Entrez Gene ID:8986
Ensembl ID:ENSG00000162302

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q11-q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 64126847 - 64138813

 Exon Info From UCSC:
NM_001006944
NM_003942

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5763859Full LengthBC047896ribosomal protein S6 kinase, 90kDa, polypeptide 4
5216639IncompleteBC028079ribosomal protein S6 kinase, 90kDa, polypeptide 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003933  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001006944 NP_001006945      
NM_003942 NP_003933 O75676 EC 2.7.11.1 Pkinase
Pkinase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF074715 AAC67395 O75676 EC 2.7.11.1
BC028079 AAH28079 A0PJF8  
BC047896 AAH47896 Q86VU2  
AK223561 BAD97281 O75676 EC 2.7.11.1
AK292163 BAF84852 O75676 EC 2.7.11.1
AK298507 BAG60713 B4DPV1  
AJ010119 CAA09009 O75676 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RPS6KA4 NP_003933 M.musculus Rps6ka4 56613 Gene Info NP_064308 96
R.norvegicus Rps6ka4 361715   NP_001101987 96
A.gambiae AgaP_AGAP006094 1276766   XP_316151 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta