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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PSMA1, proteasome (prosome, macropain) subunit, alpha type, 1
Sequence ID:NM_001143937
Entrez Gene ID:5682
Ensembl ID:ENSG00000129084

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 14526674 - 14541932

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3140784Full LengthBC002577proteasome (prosome, macropain) subunit, alpha type, 1
3452219Full LengthBC015356proteasome (prosome, macropain) subunit, alpha type, 1
3950568Full LengthBC015105proteasome (prosome, macropain) subunit, alpha type, 1
4078894Full LengthBC005932proteasome (prosome, macropain) subunit, alpha type, 1
4105838Full LengthBC009576proteasome (prosome, macropain) subunit, alpha type, 1
4282076Full LengthBC008472proteasome (prosome, macropain) subunit, alpha type, 1
4770620Full LengthBC022372proteasome (prosome, macropain) subunit, alpha type, 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_683877  NP_002777  

Protein Infomation

NM_001143937 NP_001137409      
NM_002786 NP_002777 P25786 EC Proteasome
NM_148976 NP_683877     Proteasome

Related Sequences

M64992 AAA92734 P25786 EC
BC002577 AAH02577 P25786 EC
BC005932 AAH05932 P25786 EC
BC008472 AAH08472 P25786 EC
BC009576 AAH09576 P25786 EC
BC015105 AAH15105 P25786 EC
BC015356 AAH15356 P25786 EC
BC022372 AAH22372 P25786 EC
BT006647 AAP35293 P25786 EC
DQ894660 ABM85586    
D00759 BAA00656 P25786 EC
AK290765 BAF83454 P25786 EC
AK303565 BAG64588 B4E0X6  
X61969 CAA43961 P25786 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PSMA1 NP_002777 M.musculus Psma1 26440 Gene Info NP_036095 98
R.norvegicus Psma1 29668   NP_058974 98
A.gambiae AgaP_AGAP010253 1279677   XP_319444 58
D.melanogaster Pros35 34359   NP_523532 56
N.crassa NCU06712 3877054   XP_960892 55
S.pombe SPAC6G10.04c 2542559   NP_594101 55
C.elegans pas-6 178943   NP_504472 54
S.cerevisiae PRE5 855362   NP_014045 53
A.thaliana PAF2 841128   NP_175158 48
A.thaliana PAF1 834290   NP_199093 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)